Chandigarh: Infertility is not one diagnosis – it is usually a multifaceted puzzle of overlapping conditions, difficult outcomes, and emotional stress. For one couple, their five-and-a-half-year journey was filled with it all: repeated IVF failures, a devastating
second-trimester miscarriage, and the emotional and physical depletion that ensued. Despite these challenging situations, the couple’s resilience took them Birla Fertility & IVF, Chandigarh, and under Dr. Rakhi Goyal expertise, they finally discovered a strategy that finally suited their individual requirements and delivered them a baby boy.
Amid multiple complexities, Birla Fertility & IVF dug deeper
The 34-year-old female had a very difficult reproductive past. She had premature ovarian insufficiency, along with adenomyosis and a unicornuate uterus, a rare congenital condition in which the uterus is half the size of a normal one, with reduced blood supply and poor implantation capacity.
In addition to this, she had a history of endometriosis and had also become pregnant on one previous occasion by donor egg IVF at a different centre. That pregnancy had ended at 22 weeks because of abruptio placentae – a serious complication which necessitated an emergency hysterotomy.
Her partner was also confronted with serious fertility issues. His semen analysis showed teratozoospermia – abnormal shape of the sperm – along with high DNA fragmentation (25%) and weak motility.
"They arrived with a folder full of diagnoses and hardly a thread of hope," Dr. Goyal said. "But their resolve stood strong and that made us to seek a course – even if it had to be created from scratch."
No shortcuts, only personalised steps
Dr. Goyal knew this case needed tailored solutions that would solve the sperm issue, prepare the uterine receptacle, handle obstetric risk, and beat emotional exhaustion at the same time.
The couple went for a repeat donor egg IVF cycle, and six good-grade blastocysts were created. But the biggest challenge was to prepare the uterus to accept the embryo. A three-month regimen of GnRH agonists was initiated to dampen uterine inflammation and increase endometrial receptivity. Meanwhile, the team also focused on optimising the patient's overall health – particularly her blood pressure, which had soared during her earlier pregnancy. Lifestyle modification, close monitoring, and supportive therapy were the mainstays.
After preparing the uterus, one top-grade Day-5 blastocyst was transferred. "Multiple embryo transfers in such situations, where the uterus is structurally weak, are dangerous. It's not only about getting pregnant; it's about making it safe," said Dr. Goyal.
The outcome was a positive pregnancy test. But the team at Birla Fertility & IVF knew that the pregnancy needed support.
Due to the patient's pregnancy and uterine condition, the pregnancy was always a high-risk one. Serial scanning showed placenta previa complicated by evidence of placenta accreta – both very serious complications which needed monitoring on an ongoing basis.
A multidisciplinary team worked together to actively manage the pregnancy. At 34 weeks, the patient gave birth to a healthy baby boy by planned caesarean section.
What made all the difference
This was not simply a medical achievement. It was a victory of personalisation, strategy, and resilience. From the meticulously-timed hormone treatment and single embryo transfer to continued risk monitoring and collaborative care – every choice was intentional, and evidence-based.
But in Dr. Goyal's opinion, the real strength of this journey lay with the couple themselves. "They had had enough setbacks to quit many times over. But they just kept coming back. Their faith gave us purpose – and ultimately, success."
A reminder that even the most difficult journeys can find the right care.
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